Trifexis for Dogs

$101.68

Quantity Discounts

Save Time and Money With Auto Ship!

Get your pet’s favorite products delivered on the schedule you set.

Save time and never run out of this item again when you schedule a recurring Auto Ship order. Auto Ship discount cannot be combined with Free Shipping.

Product Details

Allow your dog to spend hours playing outside without worrying that he/she will become infected with heartworms, fleas, and intestinal worms. Trifexis is a chewable tablet that you can give once a month in order to kill fleas, prevent flea infestations, protect against heartworm disease, and treat/control adult hookworm, roundworm, and whipworm infections.

What is Trifexis? Trifexis is an oral preventative medication that can be given every 30 days to provide protection against fleas, heartworm, disease, and common intestinal parasites. It works to kill fleas, prevent flea infestations, protect against heartworm disease, and treat/control adult hookworm, roundworm, and whipworm infections.

Formulated for: dogs and puppies. Puppies need to be 8 weeks of age or older and must weigh 5 lbs or more in order to receive this medication safely.

How does this medication work? Milbemycin oxime and spinosad are the main ingredients that help to protect your dog from heartworms, fleas, and intestinal parasites. Milbemycin oxime works to help prevent heartworm disease. It works to kill the immature form of the heartworm (Dirofilaria immitis) before heartworms have the chance to develop into adults that can cause active disease. Milbemycin is also effective in killing common adult intestinal parasites (hookworms, roundworms, and whipworms) that can cause problems in your dog. Spinosad helps to kill fleas and prevent future flea infestations by killing adult fleas and immature fleas.

What results can I expect? Trifexis works almost immediately. It starts to kill fleas within 30 minutes and can kill 100% of all biting fleas within 4 hours. It is also effective in killing flea eggs which interrupts the flea life cycle. Trifexis also prevents heartworm disease by killing microfilariae and larvae. This prevents them from developing into adults. You can also expect Trifexis to help treat and control roundworms, hookworms, and whipworms.

What Form(s) does Trifexis come in? This medication is a tablet that is flavored and chewable.

Generic Name: Milbemycin oxime plus spinosad (Common Drug Name)

Common Brand Name: Trifexis (Elanco).

Drug and Food Interactions: Always tell your veterinarian about any medications, vitamins, or supplements your dog is taking before you start giving him/her Trifexis. Some serious adverse reactions have been documented when spinosad and ivermectin at doses higher than the heartworm prevention dose were used simultaneously. No known food interactions have been reported.

Uses: Trifexis is given to dogs one time per month in order to prevent heartworm disease, kill fleas, prevent flea infestations, and treat/control adult hookworm, roundworm, and whipworm infections.

Possible Side Effects: If using Trifexis at the recommended dosage, side effects are rare. Symptoms of gastrointestinal distress and skin irritation can occur. Vomiting, diarrhea, lethargy (decreased activity), lack of appetite, and itching and reddening of the skin are possible. If you observe any of these signs or any unusual symptoms in your dog once Trifexis has been administered, contact your veterinarian immediately. Vomiting may be more likely in puppies under 14 weeks of age. If your dog is truly allergic to Trifexis or to the dying of parasites, he/she may exhibit symptoms such as facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. If your dog experiences any of these symptoms, call your veterinarian or a local emergency veterinarian immediately.
  • Protects against 5 different types of parasites: fleas, heartworms, roundworms, hookworms, and whipworms.
  • Kills fleas and helps to prevent flea infestations.
  • Combination of 2 active ingredient helps to keep your dog well protected.
  • Tablets are chewable and flavored allowing for easy administration.
  • Orally administered so there is no mess and no stress that other pets can lick medication.

Dose and Administration: Trifexis is a chewable tablet that should be given by mouth (orally) with food in order to achieve the maximal effect. It is given once a month seasonally or year-round. Try to administer each dose on the same day every month.

Follow your veterinarians instructions regarding the use of Trifexis. Generally, Once a month administration is what is most common. You may be directed to give this medication every month or just in warm months when mosquitoes and fleas are most prevalent. There are several sizes of this medication available that are based on your dogs body weight.

If you are giving Trifexis seasonally, it should be administered during and 3 months beyond the mosquito season, preferably on the same date each month. Treatment with less than 3 monthly doses after the last exposure to mosquitoes may not be effective.

This medication should not be given to any dogs other than the one that your veterinarian prescribes it for. Do not split tablets.

If you miss a dose, give it as soon as you remember. If more than one month has passed since the last dose of Trifexis, check with your veterinarian as a repeat heartworm test may be necessary.

Contact your veterinarian regarding Trifexis if you have further questions or if you are not sure how to administer this medication properly.

Storage: This medication should be stored in a tight, light-resistant, childproof container at room temperature. Keep out of reach of children and pets.

A prescription from your veterinarian is required to purchase Trifexis.
SKU: 51082

Buy More Save More!

Reviews

REVIEW SNAPSHOT®

by PowerReviews
Trifexis for Dogs
 
4.4

(based on 24 reviews)

Ratings Distribution

  • 5 Stars

     

    (14)

  • 4 Stars

     

    (8)

  • 3 Stars

     

    (1)

  • 2 Stars

     

    (0)

  • 1 Stars

     

    (1)

96%

of respondents would recommend this to a friend.

Pros

  • Easy to use (19)
  • Effective (17)
  • Long-lasting (13)
  • No side effects (13)
  • Gentle (11)

Cons

  • Difficult to administer (5)

Best Uses

  • Younger pets (4)
  • Daily care (3)
    • Reviewer Profile:
    • Long-time pet owner (22)

Most Liked Positive Review

 

Trifexis

My big dog has been on Trifexis for several years and he has never had any side effects from it. It is a bit expensive from my vet and I am going to start...Read complete review

My big dog has been on Trifexis for several years and he has never had any side effects from it. It is a bit expensive from my vet and I am going to start ordering it online.
The only negative thing I can say about this medication is, my dog hates the taste and won't chew it. My dog eats dry dog food but every month I have to give him wet dog food with the Trifexis tablet crushed up and mixed in it. This is the only way he will eat it.
It would be nice if this medication would come in a capsule so I could just have my dog swallow it.

VS

Most Liked Negative Review

 

Not effective, Elanco no help

We have been giving our 11 month old mix Trifexis at the recommendation of our vet since we have had him (6 months). Two weeks after his latest dose, he was seeming lethargic...Read complete review

We have been giving our 11 month old mix Trifexis at the recommendation of our vet since we have had him (6 months). Two weeks after his latest dose, he was seeming lethargic and we needed a new box of Trifexis, so we decided to take him in for the regular check-up he was slightly overdue for. At the check-up, his fecal came back positive for hookworms; thinking that surely Elanco's satisfaction guarantee would cover treatment, we gave him a prescription of Drontal ($56) at our vet's recommendation. Now, after both myself and my vet have talked to the Elanco rep, we have been told that Elanco will not honor any guarantee since the infection was discovered as part of a regular check-up. I understand that the worm has a short cycle and it is possible that he could test positive that soon after a dose, but based on his possible exposure I find it unlikely (clean yard) and the reaction of Elanco has left me extremely displeased. We will not continue treating with Trifexis, and I certainly would not recommend the product to others.

Reviewed by 24 customers

Displaying reviews 1-5

Back to top

Previous | Next »

(0 of 1 customers found this review helpful)

 
5.0

I would keep buying this product

By Mita

from Florida

About Me Long-time Pet Owner

Pros

  • Effective
  • No Side Effects

Cons

    Best Uses

      Comments about Trifexis for Dogs:

      You just give it to your dog once a month and it takes care of fleas, ticks and heart worms. Fantastic!

      Comment on this reviewHelp Icon

      (0 of 1 customers found this review helpful)

       
      5.0

      Trufexis

      By Fenster

      from Chicago

      About Me Long-time Pet Owner

      Pros

      • Easy To Use
      • Effective
      • Gentle
      • Long-Lasting
      • No Side Effects

      Cons

        Best Uses

          Comments about Trifexis for Dogs:

          Easy once a month oral that dog chews happily. Effective for heartworm and ticks

          Comment on this reviewHelp Icon

           
          5.0

          Trifexis!

          By Dallas the Lab

          from Mission, Texas

          About Me Long-time Pet Owner

          Pros

          • Easy To Use
          • Effective

          Cons

            Best Uses

            • Daily Care

            Comments about Trifexis for Dogs:

            Easy to use, works good!

            Comment on this reviewHelp Icon

            (1 of 1 customers found this review helpful)

             
            5.0

            medication

            By the maestro

            from sunny florida

            About Me Professional Pet Trainer

            Pros

            • Easy To Use
            • Gentle
            • No Side Effects

            Cons

              Best Uses

              • Older Pets
              • Younger Pets

              Comments about Trifexis for Dogs:

              very easy to give put a drop of gravy on it

              Comment on this reviewHelp Icon

              (1 of 2 customers found this review helpful)

               
              3.0

              I assume it works.

              By Don't have one

              from Tampa, Fla.

              About Me Long-time Pet Owner

              Pros

              • Easy To Use
              • Long-Lasting

              Cons

                Best Uses

                  Comments about Trifexis for Dogs:

                  My vet recommended this, so I assume it's good, but someone at the dog park said she'd never give it to her dogs, based on someone else's supposed bad experience. But that's just secondhand hearsay. I'm still using it.

                  Comment on this reviewHelp Icon

                  Displaying reviews 1-5

                  Back to top

                  Previous | Next »