What is Temaril-P? a combination medication that contains trimeprazine and prednisolone to stop itching and coughing associated with allergies in dogs.
Formulated for: dogs
How does this medication work? The combined action of the antihistamine, trimeprazine, and the corticosteroid, prednisolone, works to decrease inflammation and block the effect of histamine in the body that contributes to itching and coughing.
What results can I expect? Temaril-P will not cure the underlying problem. It will, however, help to relieve coughing, inflammation, and itching of the skin that may occur as a result of common conditions including kennel cough (tracheobronchitis), bronchitis/coughs of nonspecific origin (except coughs due to cardiac insufficiencies), and itching that may result from eczema, otitis, and dermatitis (allergic, parasitic, pustular and non-specific).
What Form(s) does Temaril-P come in? scored tablets.
Generic Name: Trimeprazine with Prednisolone (active ingredients). No generic products are available. Compounded products may be available.
Common Brand Name: Temaril-P (Pfizer Animal Health)
Dose and administration: Temaril-P is available by prescription as scored tablets that contain a combination of trimeprazine (5mg) and prednisolone (2mg). The standard dosage is based on body weight. Exact duration and dosage will be determined by your veterinarian.
There should be a gradual reduction in dosage before stopping. Temaril-P should be taken with food to lessen stomach upset. Make sure your pet has access to water continuously while taking this medication. If a dose is missed, give it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to the regular schedule. Do not give two doses at once.
Uses: Used to relieve irritation of the throat that causes coughing from allergic bronchitis, infections, or coughs of non-specific origin. This medication is also commonly prescribed for itching and inflammation of the skin and ear.
Possible side effects: Side effects are usually dose dependent. If side effects occur, contact your veterinarian, who may decrease the dosage or frequency of administration or discontinue this medication. Side effects may include sedation, exposed third eyelid, muscle tremors, weakness, blood disorders, and an increase in drinking, eating, and urinating. Your pet may have more "accidents" and need to go outside or use the litter box more often. Less common side effects include increased appetite, weight gain, panting, diarrhea, vomiting, and behavior changes.
Side effects of long-term use include muscle loss, weakness, and the development of diabetes or hyperadrenocorticism (Cushing's disease). The typical signs of these diseases are increased thirst, urination, and appetite. Animals with Cushing's disease may also develop thin skin, a poor hair coat, and a distended abdomen.
Longer term use of Temaril-P can also cause immune system suppression, especially at higher doses, making a pet more susceptible to infection. Contact your veterinarian if your pet displays symptoms of infection including: fever (over 103 degrees F), painful urination (a sign of urinary tract infection), tiredness, and sneezing, coughing, or runny eyes.
Signs of an allergic reaction may include facial swelling, hives, scratscratching, diarrhea, vomiting, shock, seizures, pale gums, cold limbs, or coma. Other side effects may occur. Any unusual behavior or symptoms should be reported to your veterinarian immediately.
Drug and Food Interactions:
- Relieves itching due to allergies in dogs and other causes of skin inflammation.
- Combination of ingredients also helps stop coughing.
- Scored tablets make giving medication to dogs of all sizes easy
Notify your veterinarian of any other medications, including vitamins and supplements, your pet is taking while your pet is receiving this medication. Drugs that may interact with Temaril-P ( trimeprazine/prednisolone) include organophosphates, procaine hydrochloride phenytoin, digitalis, epinephrine, phenobarbital, amphotericin B, rifampin cyclosporine, estrogens, erythromycin, mitotane, quinidine, sedatives, general anesthetics, pain medications, Pepto-Bismol, other antidiarrheal mixtures, and antacids.
The risk of ulcers is increased with nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin, carprofen (Rimadyl), deracoxib (Deramaxx), or etodolac (EtoGesic). Insulin requirements may also increase in diabetic animals. Corticosteroids can cause abnormal levels of liver enzymes, thyroid hormone, cholesterol, and potassium in the blood. Regular blood tests may be necessary if your pet is taking Temaril-P for prolonged periods.Precautions:
Tell your veterinarian if your pet has diabetes, stomach ulcers, Cushings disease, infection, heart, liver or kidney disease. Consult your veterinarian if your pet may be pregnant or is nursing. These conditions may be worsened by the administration of Temaril-P. Notify your veterinarian of any other medications or supplements your dog is taking. Reactions to any previous medications should also be reported to your veterinarian.Storage:
Store Temaril-P in a tight, light-resistant, childproof container at room temperature. Keep away from children and pets.A prescription from your veterinarian is necessary to purchase Temaril-P for your dog.