What is Humulin N insulin? a hormone used for the treatment of diabetes mellitus. It is a type of human insulin that often works well in treating diabetes mellitus in dogs too. It is a crystalline suspension with protamine and zinc. It is immediate-acting insulin which means that it is slower in onset and lasts longer (up to 24 hours).
Formulated for : humans but is commonly used to treat dogs with diabetes mellitus. It is sometimes used for cats too but this is less common.
How is this medication given? It is an injectable medication, generally given by subcutaneous injection (under the skin). Humulin N insulin is used to help control blood glucose levels in diabetic pets. The amount and frequency that your pet needs is individual and will be determined by your veterinarian. It is given once a day or twice a day based on your veterinarian’s recommendation. Just prior to use, mix the vial gently rolling it between the palms of your hands approximately 10 times. Humulin N must be used with a U-100 insulin syringe only. Use of an insulin syringe other than U-100 will result in incorrect dosing.
How does this medication work? Insulin is a hormone that is naturally produced by the pancreas. Humulin N mimics the insulin that is normally produced. Pets with diabetes mellitus do not produce enough insulin on their own to control their blood sugar (glucose). This results in hyperglycemia (high blood sugar). Humulin N controls hyperglycemia and helps relieve the symptoms of diabetes mellitus in dogs.
What results can I expect? Insulin is not a cure for diabetes. It will, however, help to bring your pet’s blood sugar to normal range. This will help manage your pet’s symptoms such as increased drinking (polydipsia) and increased urination (polyuria)
What Form(s) does Humulin N come in? a liquid, injectable medication available in 10 mL vials containing 100 units per mL.
Generic Name : NPH human insulin
Common Brand Name: Humulin-N (Lilly)
Dose and Administration : Humulin N is a human insulin. It is not FDA approved for use in veterinary medicine but it is a commonly accepted practice for veterinarians to use this medication in dogs and cats. It is very important to follow your veterinarian’s precise instructions regarding this medication. The dose of Humulin N insulin is determined by means of a blood glucose test and is individual for your pet. Do not give your pet an injection of this or any other medication unless you have been trained on how to do so by your veterinarian.
Doses can vary and will be determined by your veterinarian. Do not shake the insulin prior to use but roll it between the palms of your hands to mix everything up. If you miss a dose of Humulin N, contact your veterinarian for further instructions.
Only use prescribed U-100 syringes (sold separately) with Humulin N or the dose will be given incorrectly.
Insulin should be given with food to make sure your pet’s blood sugar does not fall too low. Your veterinarian will instruct you on the best diet and exercise plan for your pet.
Possible Side Effects: Side effects may include weakness, tiredness, shaking, seizures or coma which may be the result of your pet’s blood sugar falling too low(hypoglycemia). Some cats may appear immobile although this is rare.
Hyperglycemia (high blood sugar) has symptoms of increased thirst and urination, vomiting, and change in gait or weakness. If you notice these symptoms once your pet’s diabetes has been regulated, the dose may need to be adjusted.
Symptoms of a true allergic reaction include facial swelling, hives, scratching, sudden onset of diarrhea, vomiting, shock, seizures, or coma. If your pet demonstrates any unusual symptoms, contact your veterinarian immediately because immediate treatment may be necessary.
Drug and Food Interactions :
- Controls your pet’s glucose levels.
- Works fast so your pets should start to feel better within a few days although results vary.
- Can be given by injection under the skin (subcutaneously) at home as directed by your veterinarian.
Tell your veterinarian about any other medications, vitamins, or supplements your pet is taking before treatment. A higher risk of low blood sugar (hypoglycemia) is possible if used with anabolic steroids, beta-blockers, monoamine oxidase inhibitors, phenylbutazone, sulfinpyrasone, tetracycline, or salicylates like aspirin. A higher risk of high blood sugar (hyperglycemia) is possible if used with glucocorticoids, thyroid medications, dobutamine, epinephrine, estrogen/ progesterone combinations, or diuretics. Hypoglycemic agents such as glipizide may help lower insulin requirements, as may chromium picolate. Caution should be used when starting treatment for thyroid disorders in a diabetic animal because insulin needs may change. Changes in potassium levels are also possible when using insulin along with heart medications and/or diuretics. If you have any questions regarding the use of insulin with other medications in your pet, consult your veterinarian.Precautions :
It will take time and multiple laboratory tests to determine the best insulin dose. Don’t make any changes to pet’s insulin regimen unless instructed to by your veterinarian as this can be dangerous. Use proper technique when giving your pet injections. It is important that you use only a U-100 syringes to avoid incorrect dosing. Make sure to follow your veterinarian’s recommendations requiring the type of food that you are feeding your pet and the time of day you are offering meals. Careful monitoring of your pet’s glucose levels is important for good results. Your veterinarian may have your test your pet’s urine or blood at home to ensure glucose levels are good. If your pet shows signs of low blood sugar, contact your veterinarian immediately.Storage:
Store unopened vials in refrigerator and opened bottles at room temperature or in refrigerator.