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SKU: RX101
RX Prescription Required
Please Note: This Item Requires a Prescription

This item is an Rx medication or Food and requires a prescription. Once you place the order, the Pet360 Pharmacist will work directly with your veterinarian to verify the prescription and dosage information.

The medication for your pet will ship within one business day of verification. It will ship from the Pet360 Pharmacy in Louisville, Kentucky.

The Pet360 Pharmacy is Vet Vipps Certified, meets or exceeds all United States veterinary pharmaceutical standards, and may legally ship to all 50 states.

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Lysodren is used to help animals who suffer from pituitary-dependent Cushing's disease (hyperadrenocorticism). This disorder results in the adrenal gland producing excess hormone and Lysodren helps to normalize hormone levels and control associated symptoms.

What is Lysodren?This is an oral tablet that treats pituitary-dependent Cushing's disease (hyperadrenocorticism). It can also be used to treat some of the symptoms associated with adrenal gland tumors.

What are the benefits of Lysodren?
  • Easy to administer with a small amount of food or treat.
  • Helps to manage pituitary-dependent Cushings disease
  • Can also help palliate some symptoms related to adrenal gland cancer

Formulated for:dogs.

How is this medication given?Give exactly according to your veterinarians instructions. It is usually recommended to give this medication with a high fat treat or food to help increase absorption.

Your veterinarian will usually start your pet on a high dose at first and then gradually decrease the dose to the minimum dose to be effective. Your veterinarian will monitor your pet closely to make sure he/she is on the correct dose of medication. If you have questions about how to use Lysodren properly, always speak with your veterinarian.

How does this medication work?With Cushing's disease and some types of tumors, excess steroid hormone is produced. Lysodren helps the adrenal gland to produce less steroid hormone so levels can return to normal.

What results can I expect? Your pets symptoms associated with Cushings disease should improve with time but the response to Lysodren is individual. If Lysodren is helping, it is usually used chronically for the rest of your pets life.

What form(s) does Lysodren come in? Tablets.

Generic Name:Mitotane(Common Drug Name)

Common Brand Name:Lysodren

Dose and Administration:Use Lysodren only as directed by your veterinarian. Lysodren is usually given with a high fat treat or some high fat food to increase absorption. Your veterinarian will monitor your pet and blood work properly to make sure they are on the proper dose of medication. If you forget to give a dose of medication, give it as soon as you remember but never double dose. Give this medication only to the pet it has been prescribed for. Always call your veterinarian if you have questions about how to use Lysodren properly.

Uses:Lysodren is used to treat pituitary-dependent Cushings disease and can also be used to treat symptoms associated with some types of adrenal tumors.

Possible Side Effects: Lethargy, weakness, lack of appetite, vomiting, diarrhea, incoordination, depression, and liver damage are possible. Your pets appetite, water intake, and urination should decrease when Lysodren starts to work.

Some pets may be truly allergic to this medication. Other side effects are possible. Call your veterinarian if your pet is acting ill while taking Lysodren.

Drug and Food Interactions: Tell your veterinarian about all other medications and supplements your pet is taking. Interactions may occur with prednisone, prednisolone, barbiturates, warfarin, phenobarbital, or spironolactone, CNS depressants, and insulin. Other drug interactions are possible.

Precautions:Do not give Lysodren to animals who are allergic to it or similar medications. Pregnant or nursing females should not be given this medication. Pregnant women should not handle this medication.

Caution should be used when giving Lysodren animals with liver or kidney disease.

Storage:Store at room temperature away from children and pets.

A prescription from your veterinarian is required to purchase Lysodren.

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This product really helped our dog


from Saylorsburg, PA

About Me Long-time Pet Owner

Verified Buyer


  • Easy To Use


    Best Uses

      Comments about Lysodren:

      This product was prescribed by our Vet. So our dog really needed it. And to save a little money we decided to use Petfooddirect's pharmacy. Whenever we call, the staff is very helpful [...] This service has worked really well for us. I recomemend giving it a try if you're interested!!



      By Marci

      from Huntingdon Valley, Penna. 19006

      About Me Long-time Pet Owner

      Verified Reviewer


      • Easy To Use
      • Effective


        Best Uses

          Comments about Lysodren:

          Product is easy to use. [...] Price is very good.

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